Important One liners

Coccidiodis immitis has more possibility of dissemination in Blood Group B individual.

Amphotericin B doesnt cross blood brain barrier so one needs to administer Fluconazole.

Meningitis is most serious problem associated with Disseminated coccioides.

Important One liners :Dermat

• Porphyria Cutanea Tarda:

4th-5th Decade
Precipitating factors:-
Alcohol,Iron, Estrogen hence birth control pills,exposure to sun
Blisters not healing or healing by scarring on sunexposed areas
Treatment;Chloroquine and phlebotomy

• Pemphigus Vulgaris:

seen in fourth-fifth decade
Skin shows autoantobodies against intercellular antigens hence shows acantholysis.

• Bullous Pemphigoid:

70-80 yrs age and Blisters at dermo-epidermal junction

Important One liners :CNS

• Myaesthenia Gravis:-
• Most accurate test of Myaesthenia gravis:- Electromyography
• Best initial and specific test:Antibody Receptor Test
• Treatment:Anticholinesterase(Pyridostigmine ) , or for non-responsive shud be given immunotherapy first being steroids in combination with azathioprine
• Acute Myasthenic Crisis:- Plasmapharesis and IV immunoglobulin
• Post-pubertal patients withage above 55 yrs are treated with thymectomy before trial of immunosuppression